Woot! again has the amazing Audyssey Desktop speakers for $79.99 with $5 shipping on everything you order. I have these speakers (and happily paid $200 for them) and they are quite simply the best desktop speakers I’ve used.
We are in love with the standalone LES powered speakers (right). Very simple I/Os and almost perfect desktop-level sound makes these incredibly good for the small room or workspace. Sure, they won’t fill up a large-sized room, but you will find much larger/expensive setups for that. $199 Amazon. Bonus: If you want Airplay functionality, throw in a $95 Apple TV and an Optical cable.
You don’t need a subwoofer and with an optical cable, I don’t think you’ll find better sound at double the price.