The good news is that today, MCE has a solution for that wasted space. They simply take your DVD-R and put it in a USB case, then put in your MacBook another hard drive inside a holder that fills the space of an optical drive. Therefore, you can technically have up to 1 TB of storage with the Unibody MacBook utilizing two 500GB hard drives space. You can even make a (assuming soft-)RAID setup.
Sweet. But we are still seeing some extra space there. How about a SD card reader and an eSATA port while you are at it!? Maybe also throw in a 3G Modem? We’ll pay the premium.